Searchable abstracts of presentations at key conferences in endocrinology

ea0015p367 | Thyroid | SFEBES2008

My brother and I–differential tissue sensitivity to thyroid hormones in thyroid hormone resistance

Lockett Helen , Stride Amanda , MacLeod Kenneth

A 62-year-old man with insulin treated type 2 diabetes presented with atrial fibrillation. Despite anticoagulation he suffered an embolic cerebellar infarct ten days later. He was found to have abnormal thyroid function tests (TSH 7.75 mu/l, free T4 49.3 pmol/l, free T3 12.0 pmol/l). Thyroid function test analysis was repeated in a second laboratory confirming the results above. TSH was stimulated by thyrotrophin releasing hormone, confirming thyroid hormone resistance. Magnet...